28 June 2011

Acne (and Rosacea) Connect to MRSA



There's growing evidence that the major source of MRSA is the inappropriate over prescribing of antibiotics by general practitioners. This may not be news and it is common knowledge that the majority of infections are viral and don't require antibiotics.

Also it is popular that antibiotics upset gut bacteria and result in overgrowth of the intestinal tract with fungi such as Candida which is present in everyone's guts, but normally held in check by the probiotic bacteria surrounding it and which also produce chemicals to keep it in check. Antibiotic use can reduce the probiotic bacteria and allow the fungus to grow which with time can lead to inflammation and misdiagnosis of IBS later in daily life and open another chapter in prescribing. A unpredictable manner we don't want to promote. Candida overgrowth and dysbiotic guts probably affect numerous '20 something's' who have just had numerous antibiotics for acne, or million of 40 something's who had been put on antibiotics for rosacea. We've got clever ways of restoring the standard bacterial balance and reducing Candida without harsh antifungals.

Though the use of antibiotics for skin ailment such as acne and rosacea often at low doses and infrequently for 3 to 6 months during a period is probably the biggest cause of MRSA (multi resistant Staphylococcus aureus) in hospitals. Let me explain.

It doesn't matter whether oral or cream antibiotics are employed they cause the same problem. In acne if you have many blocked 'pores' (pilo sebaceous ducts) then your anaerobic bacteria propiobacterium acnes (p.acnes) can start to colonise the region under the plug and cause inflammation and damage. This bacterium only survives in normal skin at very low levels as it likes to have a home in an environment where there is minimum oxygen. When you create a blockage similar to acne, you create the earth for p.acnes. So antibiotics will help reduce p.acnes, but they also hit other friendly skin bacteria and herein lies the problem.

Staphylococcus epidermidis (s.epidermidis) lives on our skin helping keep other nasty bacteria away. It likes an oxygen rich environment. A similar antibiotics that reduce p.acnes often hit the s.epidermidis too. This attack puts selective pressure within the bacteria to survive and within 3 to 4 weeks you can isolate resistant strains s.epidermidis on skin receiving treatment with antibiotics.

Now Staphylococcus epidermidis is related to Staphylococcus aureus (s.aureus) (cousins if you like). S. aureus lives from the body and s.epidermidis lives on the skin. They meet at places such as nose and other entrances to the body. They can pass information together through the use of things called plasmids in fact it is highly likely information for developing resistance is transferred.

Hey presto we now have started the super bug development. The acne sufferer ends up in hospital for an operation. They get a wound infection either from other own bacteria but also through other bugs already there. S.aureus is a typical bacterium that infects wounds. The antibiotics used in wound infections are often a similar or similar to the one that has been utilized for the patient's acne, and it is wonder they find the antibiotics don't are the the bugs are already resistant. This resistant strain becomes the dominant resident s.aureus in the hospital and is extremely difficult to remove and can go on to infect several patients.

Using a product such as Aknicare which has 4 antibacterial agents which control p.acnes by changing conditions in the area under the plug rather than directly destroying this would mean you can prevent damage and inflammation without breeding resistant bugs. Aknicare helps to reduce p.acnes and all the other key reasons for an acneic skin (inflammation, oil production, cell turnover) all without breeding resistant bugs.

Like a final thought the main strategy for rosacea recommended on PRODIGY, the GP prescribing database recommends ROSEX lotions. Rosex contains the antibiotic metronidazole. Rosacea patients often use it for months and years. It functions in a few. Metronidazole is also a powerful antioxidant in fact it is these properties that help with rosacea symptoms, not the antibiotic properties. Rosacea isn't caused by bacteria. It is a sobering considered that the antibiotic most utilised in theatre to prevent infections during and shortly after surgery is metronidazole. Imagine if you had been using it for time before that operation.

It truly is concerning to think the antibiotic you're using today could end up leading to someone dying in hospital before i write again. Change prescribing habits for acne and rosacea now and have absolutely an impact on MRSA in hospitals.

Use Aknicare, a new medical device with a CE mark . Once in the drug tariff this should be prescribed by GPs. PCTs should take action now

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